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atpI [2019-08-12 10:03:54]
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atpI [2019-08-12 10:03:54]

ATP synthase (subunit i)
locus
BSU_36880
pI
10.16
mw
14.35 kDa
protein length
127 aa Sequence Blast
gene length
384 bp Sequence Blast
function
ATP synthesis
product
ATP synthase (subunit i))
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.5|ATP synthesis] → [category|SW 2.1.5.1|ATPase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,787,620 3,788,003

    The protein

    Catalyzed reaction/ biological activity

  • ATP synthesis [http://www.youtube.com/watch?v=uOoHKCMAUMc see a video]

    • Protein family

  • bacterial atpI family (single member, according to UniProt)

    • Effectors of protein activity

  • ATPase activity is inhibited upon binding of Mg-ADP to [protein|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|AtpD] [pubmed|30580998]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]-[gene|CC1894D90AC17487A286B2909964916825055F93|atpB]-[gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]-[gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]-[gene|E956A30D97B2941108880F3AD48620C4DB6E0EBD|atpH]-[gene|E3FADE979CE6AB6315F67812608FCE00CF4E2453|atpA]-[gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]-[gene|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|atpD]-[gene|A9DA64F8C7A60E8E2B1EDC99BEA1BD7DD0135AA6|atpC]
    description
    [Pubmed|9353933]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]

    • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • the mRNA is processed between [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI] and [gene|CC1894D90AC17487A286B2909964916825055F93|atpB] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]
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    Biological materials

    Mutant

  • BKE36880 ([gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTATCTGTCTCCTG, downstream forward: _UP4_TCAATGGAAGAGAGGTGAAA
  • BKK36880 ([gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTATCTGTCTCCTG, downstream forward: _UP4_TCAATGGAAGAGAGGTGAAA

    • References

  • 7961438,29794222,30580998